The Chemical Biology in Translation (CBIT) Program of the Institute for Translational Medicine and Therapeutic (ITMAT) announces it first round of successful applications for High Throughput Screening (HTS). A second competition will be announced in June of 2007.
CBIT’s mission is to work with Penn, CHOP, and Wistar scientists to screen biological targets of clinical relevance against chemical libraries through the use of robotic instrumentation. Small molecules identified through HTS are then subject to hit-to-lead optimization chemistry. CBIT is co-directed by Drs. Scott L. Diamond and William DeGrado.
RecipientsGary D. Kao, M.D., Ph.D.
Detection of caspase activation in zebrafish embryos, a sophisticated vertebrate for high-througput screening (HTS) of radiomodifying agents
Emer M. Smyth, Ph.D.
Identifying selective ligands for prostacyclin-thromboxane receptor heterodimerss
