Day 1 – May 5, 2006
Morning
7:30 AM Registration: Lobby
8:45 AM Introduction: Arthur Rubenstein, MB, BCh, Executive Vice President of the University of Pennsylvania for the Health System and Dean of the School of Medicine
Session One: Translational Research in Academia
Chairs: Dan Rader, M.D., Associate Professor of Medicine, Associate Director of ITMAT, University of Pennsylvania and Carl June M.D., Professor, Department of Pathology and Laboratory Medicine, University of Pennsylvania
9:00 AM Edward Holmes, M.D., Vice Chancellor, UCSD (University of California, San Diego)
"The College of Integrated Life Sciences: an Academic Model for Fostering Translational Research"
9:40 AM Barry Coller, M.D., Physician in Chief, Rockefeller University
"αllb β3 Antagonists As An Example of Translational Medicine Therapeutics"
10:15 – 10:45 BREAK
10:45 AM Alastair Wood, M.D., Associate Dean, Vanderbilt University School of Medicine
"Prescribing By Genotype Are We There Yet?"
11:15 AM Kathy High, M.D., Ph.D., Investigator, HHMI, University of Pennsylvania School of Medicine
"Cell and Gene Therapies: Challenges in Developing Paradigms for Analyzing Novel Therapeutics"
12:00 – 1:30 LUNCH
Afternoon
Session Two: Opportunities for Translational Research in the Region
Chairs: Paul Blake, FRCP, Executive Vice President, Worldwide Medical and Regulatory Operations, Cephalon Corporation and Glen Gaulton Ph.D., Vice Dean for Research and Research Training, University of Pennsylvania
1:30 PM Garret FitzGerald, M.D., Director, ITMAT, Chair, Department of Pharmacology, University of Pennsylvania
"The Emerging Era of Translational Medicine and Therapeutics"
2:00 PM Walter Koch, Ph.D., Director, Center for Translational Medicine, Thomas Jefferson University
"Translational Studies in Heart Failure"
2:40 PM Ellen Puré, Ph.D., Wistar and Ludwig Institutes
"Today's Discoveries, Tomorrows Cures? A Convergence of Cultures"
3:15 – 3:45 BREAK
3:45 PM J. Richard Landis, Ph.D., Professor of Biostatistics, University of Pennsylvania
"Integrated Clinical Research Informatics for Translational Medicine and Therapeutics"
4:15 PM J. Robert Beck, M.D., Vice President and Deputy Director of Population Science, Fox Chase Cancer Center
"The Greater Philadelphia Bioinformatics Alliance: Technology Collaboration for Training and Discovery"
Evening
7:00 PM RECEPTION AND DINNER – The College of Physicians of Philadelphia
  Introductory Remarks: Governor Edward Rendell, Governor of the State of Pennsylvania
After Dinner Speaker: Arthur Caplan, Ph.D., Chair, Department of Bioethics, University of Pennsylvania
"Ethical Challenges Facing Translational Research: What Can, Should and Must Be Done?"
Day 2 – May 6, 2006
Morning
8:00 AM Registration: Lobby
Session One: Fostering and Regulating Translational Research: A Global Perspective
Chairs: Desmond Fitzgerald M.D., University College Dublin and Dr. Melanie Brazil, Biopharma Publisher, Nature Publishing Group
9:00 AM Mary Harney, TD, Tánaiste and Minister for Health and Children, Government of Ireland
"Fostering Innovation: A Government Perspective"
9:30 AM Janet Woodcock, M.D., Acting Deputy Commissioner for Operations, FDA
"FDA’s Critical Path Initiative and Translational Research"
10:15 – 10:45 BREAK
10:45 AM Sir Colin Dollery, M.D., Senior Advisor, GlaxoSmithKline
"Revitalising Clinical Investigation, Who, How and Where?"
11:15 AM Sophia Tickell BA, Director of Pharma Futures II, and Chair, SustainAbility
"Making Pharma Sector Investment More Attractive – Why the Business Model Needs to Change?"
12:00 – 1:00 LUNCH
Afternoon
Session Two: Revising the Business Model: Translational Research and Drug Development
Chairs: Sir Keith Peters FRS, GlaxoSmithKline and Christopher Bowe, Financial Times US Pharmaceuticals/Healthcare Correspondent
1:00 PM Thomas Caskey, M.D., Managing Director, Cogene Ventures
"Improving Drugs and Development by Technology Advancements"
1:30 PM George Yancopoulis, M.D., Ph.D., Chief Scientific Officer, Regeneron
"VEGF Trap in Clinical Trials Today, and VelociGene Coupled with Veloclmmune for Drug Targets of Tomorrow"
2:00 PM Mark Fishman, M.D., Ph.D., President, Novartis Institutes for BioMedical Research (NIBR)
"Pharma at the Frontier"
2:30 – 3:15 BREAK
3:15 PM F.M. Scherer, MBA, Ph.D., Aetna Professor Emeritus, John F Kennedy School of Government, Harvard University
"Sustaining the Golden Age: An Economic Perspective"
3:45 PM Jerome Strauss, M.D., Ph.D., Dean VCU School of Medicine, Virginia Commonwealth University
"Labors of Love: Science Serving The Public Good"
4:15 PM Conclusion