| Day 1 – May 5, 2006 |
|
Morning |
| 7:30 AM |
Registration: Lobby |
| 8:45 AM |
Introduction:
Arthur Rubenstein, MB, BCh, Executive Vice President of the University of Pennsylvania for the
Health System and Dean of the School of Medicine |
|
Session One: |
Translational Research in Academia |
|
Chairs:
| Dan Rader, M.D., Associate Professor of Medicine, Associate Director of ITMAT, University of Pennsylvania and Carl June M.D., Professor, Department of Pathology and Laboratory Medicine, University of Pennsylvania
|
|
9:00 AM |
Edward Holmes, M.D., Vice Chancellor, UCSD (University of California, San Diego)
"The College of Integrated Life Sciences:
an Academic Model for Fostering Translational
Research" |  |
 |
|
9:40 AM |
Barry Coller, M.D., Physician in Chief, Rockefeller University
"αllb β3 Antagonists As An Example of Translational Medicine Therapeutics" |
 |
 |
|
10:15 – 10:45 |
BREAK |
|
10:45 AM |
Alastair Wood, M.D., Associate Dean, Vanderbilt University School of Medicine
"Prescribing By Genotype Are We There Yet?" |
 |
|
11:15 AM |
Kathy High, M.D., Ph.D., Investigator, HHMI, University of Pennsylvania School of Medicine
"Cell and Gene Therapies:
Challenges in Developing Paradigms for Analyzing Novel
Therapeutics" |  |
|
12:00 – 1:30 |
LUNCH |
|
Afternoon |
|
Session Two: |
Opportunities for Translational Research in the Region
|
|
Chairs: |
Paul Blake, FRCP, Executive Vice President, Worldwide Medical and Regulatory Operations, Cephalon Corporation
and Glen Gaulton Ph.D., Vice Dean for Research and Research Training, University of Pennsylvania |
|
1:30 PM |
Garret FitzGerald, M.D., Director, ITMAT, Chair, Department of Pharmacology, University of Pennsylvania
"The Emerging Era of Translational Medicine and Therapeutics" |  |
 |
|
2:00 PM |
Walter Koch, Ph.D., Director, Center for Translational Medicine, Thomas Jefferson University
"Translational Studies in Heart Failure" |  |
|
2:40 PM |
Ellen Puré, Ph.D., Wistar and Ludwig Institutes
"Today's Discoveries, Tomorrows Cures?
A Convergence of Cultures" |  |
| 3:15 – 3:45 |
BREAK |
|
3:45 PM |
J. Richard Landis, Ph.D., Professor of Biostatistics, University of Pennsylvania
"Integrated Clinical Research
Informatics for Translational Medicine and Therapeutics" |  |
|
4:15 PM |
J. Robert Beck, M.D., Vice President and Deputy Director of Population Science, Fox Chase Cancer Center
"The Greater Philadelphia Bioinformatics Alliance: Technology Collaboration for Training and Discovery" |  |
|
Evening |
|
7:00 PM |
RECEPTION AND DINNER – The College of Physicians of Philadelphia |
| |
Introductory Remarks: Governor Edward Rendell, Governor of the State of Pennsylvania
After Dinner Speaker: Arthur Caplan, Ph.D., Chair, Department of Bioethics, University of Pennsylvania
"Ethical Challenges Facing Translational Research: What Can, Should and Must Be Done?" |
| Day 2 – May 6, 2006 |
|
Morning |
| 8:00 AM |
Registration: Lobby |
|
Session One: |
Fostering and Regulating Translational Research: A Global Perspective |
|
Chairs:
| Desmond Fitzgerald M.D., University College Dublin and Dr. Melanie Brazil, Biopharma Publisher, Nature Publishing
Group |
|
9:00 AM |
Mary Harney, TD, Tánaiste and Minister for Health and Children, Government of Ireland
"Fostering Innovation: A Government Perspective"
|  |
|
9:30 AM |
Janet Woodcock, M.D., Acting Deputy Commissioner for Operations, FDA
"FDA’s Critical Path Initiative and Translational Research"
|  |
 |
|
10:15 – 10:45 |
BREAK |
|
10:45 AM |
Sir Colin Dollery, M.D., Senior Advisor, GlaxoSmithKline
"Revitalising Clinical
Investigation, Who, How and Where?"
|  |
|
11:15 AM |
Sophia Tickell BA, Director of Pharma Futures II, and Chair, SustainAbility
"Making Pharma Sector Investment More Attractive – Why the Business Model Needs to Change?" |  |
|
12:00 – 1:00 |
LUNCH |
|
Afternoon |
|
Session Two: |
Revising the Business Model: Translational Research and Drug Development |
|
Chairs: |
Sir Keith Peters FRS, GlaxoSmithKline and Christopher Bowe, Financial Times US Pharmaceuticals/Healthcare Correspondent |
|
1:00 PM |
Thomas Caskey, M.D., Managing Director, Cogene Ventures
"Improving Drugs and Development by Technology Advancements"
|  |
 |
|
1:30 PM |
George Yancopoulis, M.D., Ph.D., Chief Scientific Officer, Regeneron
"VEGF Trap in Clinical Trials Today,
and VelociGene Coupled with Veloclmmune for Drug
Targets of Tomorrow"
|  |
|
2:00 PM |
Mark Fishman, M.D., Ph.D., President, Novartis Institutes for BioMedical Research (NIBR)
"Pharma at the Frontier"
|  |
 |
| 2:30 – 3:15 |
BREAK |
|
3:15 PM |
F.M. Scherer, MBA, Ph.D., Aetna Professor Emeritus, John F Kennedy School of Government,
Harvard University
"Sustaining the Golden Age: An Economic Perspective"
|
|
3:45 PM |
Jerome Strauss, M.D., Ph.D., Dean VCU School of Medicine, Virginia Commonwealth University
"Labors of Love: Science Serving The Public Good"
|  |
|
4:15 PM |
Conclusion
|