Center for Biomedical Informatics in Translation (BIIT)

The Center for Biomedical Informatics in Translation (BIIT) coordinates biomedical informatics for ITMAT, the academic home of Penn's CTSA. BIIT promotes strong collaboration among all informatics groups within Penn, The Children's Hospital of Philadelphia (CHOP) and the University of Pennsylvania Health System (UPHS), catalyzing the pursuit of enterprise-wide transformational goals.

BIIT has been promoting enterprise-wide transformational strategic planning and institutional developments, while also focusing on the practical applied informatics needs of research investigators. In particular, resource development efforts are being targeted towards essential informatics infrastructure and applied informatics services for the wider research community.

The Co-Directors of BIIT (JR Landis–PENN & P White–CHOP) are committed to promote strong cooperation among all informatics groups within both institutions, recognizing that the transformational goals cannot be attained without strong partnership between both institutions. J Kim, PhD, Prof of Biology, Co-Director, Penn Genome Frontiers Institute (PGFI) is BIIT Associate Director. This leadership team for BIIT spans the broad domains of Penn Medicine, CHOP and the campus-wide PGFI. This cooperation is further strengthened by close alignment with the Biomedical Data Coordinating Core (BDCC) within the Abramson Cancer Center, also directed by JR Landis.

The goals for BIIT are to:

  1. provide resources for developing novel methods and approaches to translational and clinical science that can be converted to knowledge;
  2. provide translational informatics technologies and a knowledge base for more effectively conducting the Penn/CHOP spectrum of clinical and translational science;
  3. foster information-driven collaboration among departments, schools, institutions, and industry, and via ITMAT to the CTSA community; and
  4. provide informatics education, training, and career development for the next generation of clinical and translational researchers.

BIIT promotes a vision for a transformed, enterprise-wide informatics framework for clinical and translational science, including:

  1. a consolidated IT data architecture, connectivity among all data repositories and research data services capacity;
  2. integrated biomedical and clinical research informatics (CRI) toolkits and expertise;
  3. promotion of standards that enable compliant interoperability, integration, and sharing of data within and between Penn Medicine and, CHOP and
  4. comprehensive research informatics and IT support for empowering statistically-based clinical and molecular analyses required for enterprise-wide science.


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