Study Design and Biostatistics (SDAB)

The Study Design and Biostatistics (SDAB) Core works closely with existing resources to provide targeted study design and biostatistics support to ITMAT/CTSA investigators. The Core serves as a direct provider of services, including protocol review, study design, proposal development, and performance of simple to potentially substantial complex analyses. SDAB integrates the support available with the HUP and CHOP Center for Human Phenomic Science (CHPSs), the expertise and resources of faculty in the Center for Clinical Epidemiology and Biostatistics / Department of Biostatistics and Epidemiology (CCEB/DBE), the Biostatistics Analysis Center (BAC), and the Biostatistics and Data Management Core (BDMC) at CHOP.

There are multiple routes to request assistance from members of the SDAB Core as shown in the figure. The primary method is to send an email to, which generates an email to Drs. Propert, Cucchiara, and Shults. The second method is via the project registration process for the BAC; requests via that route are triaged and forwarded to Dr. Propert if ITMAT-related. Direct contact to SDAB personnel is also commonly used, especially for projects for which a previous collaboration exists. Regardless of the initial route of contact, all requests are reviewed and needs for faculty participation, design and/or data analysis assistance, and data management assessed. Any investigator requesting core support will need to be a registered ITMAT member and the proposed project will need to meet criteria of being a CTSA-appropriate project. Emphasis is placed on projects in accord with the two overarching themes of our CTSA – Translational Therapeutics and Bridging the Pediatric to Adult divide.


SDAB Core Director: Kathleen Joy Propert, ScD

Adult: Andy Cucchiara, PhD

Pediatric: Abbas Jawad, PhD