ITMAT in the News
Penn Medicine and LouLou Foundation Create Program of Excellence for Rare Genetic Disorder that Affects Children
Friday, February 5, 2016
The London-based LouLou Foundation and the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania have established a Program of Excellence to develop effective treatments for children with CDKL5, a rare X-chromosome-linked genetic disorder that causes severe neuro-developmental impairment and early-onset, difficult-to-control seizures.
Tuesday, February 2, 2016
A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists from the Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia (CHOP).
Tuesday, February 2, 2016
For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases in cancer and tissue degeneration, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
Monday, February 1, 2016
For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected.
Monday, January 25, 2016
A decades-long mystery of how the cell’s powerhouse, and its energy currency of calcium ion flow, is maintained under different physiological conditions has been solved by researchers from the Perelman School of Medicine at the University of Pennsylvania.
Powerful Machine-Learning Technique Uncovers Unknown Features of Important Bacterial Pathogen, According to Penn Study
Wednesday, January 20, 2016
A powerful new machine-learning technique can be applied to large datasets in the biological sciences to uncover previously unknown features of organisms and their genes, according to a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.
Friday, January 15, 2016
In a recently published study in Cancer Biology and Therapy, a group of Penn colleagues used a version of the PathoChip microarray, which contains 60,000 probes for all known viruses, as well as a broad range of bacteria, protozoa, fungi, and helminthes, a parasitic worm, to identify the pathogenic agent in the sample of a patient.
New Understanding of Knee Fibrocartilage Structure Could Aid in Development of Better Replacements and Injury Treatments
Friday, January 8, 2016
Fibrocartilage tissue in the knee is comprised of a more varied molecular structure than researchers previously appreciated, according to a new study by researchers from the Perelman School of Medicine at the University of Pennsylvania and the University of Delaware.
Monday, January 4, 2016
In a new study published today in Science, a multi-institution team anchored at University of Pennsylvania found that caste-specific behaviors of carpenter ants are not set in stone.
Monday, December 14, 2015
The presence or absence of the CAP2 gene causes sudden cardiac death in mice, according to new research from the Perelman School of Medicine at the University of Pennsylvania.