Cardiovascular Phenotyping Unit

The Cardiovascular Phenotyping Unit provides cardiac testing services with shared facilities for both children and adults. The Unit provides the technical services and expertise to conduct the highest quality research, provides research tests in a cost-effective manner, and provides unparalleled training opportunities in clinical research for investigators, fellows, students and technicians. Most services are provided across the life cycle.  For studies involving both adult and pediatric populations, the pediatric and adult CPUs can collaborate closely and standardize procedures according to the investigators’ needs. Please contact the Directors for special arrangements or input regarding cardiovascular phenotyping.

Services - Penn Presbyterian Medical Center (PPMC)

  • Resting ECG
  • 2D Echocardiogram
  • 3D Echocardiogram
  • Echocardiogram quantitation and interpretation
  • Stress echocardiography
  • Stress echocardiography interpretation
  • Non-clinical Stress ECG
  • Stress ECG interpretation
  • Tests of vascular structure/function, with prior approval
  • Cardiopulmonary Exercise Testing (CPET), including VO2 measurements 
  • Cardiopulmonary Exercise Testing (CPET) + Echocardiography combined studies
  • Treadmill or bike testing (Submaximal or Maximal), with ECG monitoring

Services - CHPS Echo Core (HUP, Ground Rhoads)

  • 2D Echocardiogram
  • 3D Echocardiogram
  • Echocardiogram quantitation and interpretation
  • Tests of vascular structure/function, with prior approval

Equipment

  • ParvoMedics True One Metabolic Measurement System (PPMC)
  • Mortara XScribe Stress Exercise Testing System (PPMC)
  • TrackMaster Treadmill (PPMC)
  • Echo GE Vivid E95 (HUP & PPMC)
  • MPI Stress ECHO Bed/Supine Cycle Ergometer (PPMC, HUP - bed only)

Contacts:

Patricia O'Brien, MSN, CRNP (PPMC)
Patricia.O'Brien@pennmedicine.upenn.edu

Amanda (Laney) Smith (HUP)
Amanda.Smith4@pennmedicine.upenn.edu

Scientific Directors:

Bonnie Ky, MD, MSCE (HUP)
bonnie.ky@pennmedicine.upenn.edu

Benedicte Lefebvre, MD (HUP)
Benedicte.Lefebvre@pennmedicine.upenn.edu

Paco E. Bravo, MD (PPMC)
Paco.Bravo@pennmedicine.upenn.edu