Center for Targeted Therapeutics and Translational Nanomedicine (CT³N)

CT3N in the News

  • Artificial Cells Can Deliver Molecules Better Than the Real Thing

    Tuesday, July 16, 2019

    From pills to vaccines, ways to deliver drugs into the body have been constantly evolving since the early days of medicine. Now, a new study from members of the lab of Virgil Percec have constructed drug delivery vehicle. The research focuses on a dendrimersome, a compartment with a lamellar structure and size that mimic a living cell. It can be thought of as the shipping box of the cellular world that carries an assortment of molecules as cargo. Their work was published in the Proceedings of the National Academy of Sciences.

  • Daeyeon Lee Wins James M. Lee Memorial Award from Korean Institute of Chemical Engineers

    Wednesday, May 1, 2019

    Daeyeon Lee, professor in the Department of Chemical and Biomolecular Engineering, has been selected by the U.S. Chapter of the Korean Institute of Chemical Engineers (KIChE) as the recipient of the 2019 James M. Lee Memorial Award. KIChE is an organization that aims “to promote constructive and mutually beneficial interactions among Korean Chemical Engineers in the U.S. and facilitate international collaboration between engineers in U.S. and Korea.”

  • Robert Carpick Named ASME Fellow

    Tuesday, April 30, 2019

    Robert Carpick, John Henry Towne Professor and Chair of Mechanical Engineering and Applied Mechanics, has been selected as a Fellow of the American Society of Mechanical Engineers (ASME). Founded in 1880, ASME is a leading engineering organization that emphasizes multidisciplinary collaboration and skill development. Of its more than 100,000 members around the world, less than 4,000 have attained the grade of Fellow.

  • Penn Immunologist and Collaborators Receive $10 Million NIH Renewal to Study Potential of Cancer-Focused Therapy on Infectious Diseases

    Thursday, April 18, 2019

    Three of the top-ten causes of death worldwide are infectious diseases, with billions of people harboring such potentially lethal pathogens as the hepatitis B virus, malaria, tuberculosis, the influenza virus, and HIV. Taking a creative approach to address this problem, Penn Medicine and colleagues at Oxford University and Massachusetts General Hospital have received an additional five-year round of funding totaling $10 million from the National Institutes of Health (NIH) to explore using a promising cancer treatment to combat these dangerous viruses. E. John Wherry, PhD, the chair of Pharmacology at the Perelman School of Medicine of the University of Pennsylvania, will lead the Penn team in the collaboration to study the impact of an immunotherapy called PD-1 blockade on viral immunity in humans. This grant renewal is part of the NIH’s Cooperative Centers for Human Immunology consortium.

  • Six Penn Medicine Physician-Scientists Elected to the Association of American Physicians

    Monday, April 8, 2019

    Six physician-scientists from the Perelman School of Medicine at the University of Pennsylvania have been elected to the Association of American Physicians, one of the nation’s most prestigious medical organizations whose members include Nobel laureates and members of the National Academy of Science and the Institute of Medicine. The Penn inductees are: Zoltan Arany, MD, PhD; Susan Domchek, MD; Scott Halpern, MD, PhD; David Margolis, MD, PhD; Maria Oquendo, MD, PhD; and Drew Weissman, MD, PhD.

  • Awards & Accolades: March 2019

    Thursday, April 4, 2019

    The Division of Chemical Toxicology of the American Chemical Society (ACS) honored Trevor Penning, PhD, the Thelma Brown and Henry Charles Molinoff Professor of Pharmacology and the director of the Center of Excellence in Environmental Toxicology, with the 2019 Founders’ Award. Penning, a professor of Biochemistry & Biophysics and of Obstetrics/Gynecology, has performed research in the areas of chemical toxicology and environmental science with over 500 publications. He studies the role of aldo-keto reductases (AKR) in hormone biosynthesis as it relates to prostate and breast cancer, as well as the development of inhibitors for AKR enzymes as chemical probes and therapeutics.

  • Ivan Dmochowski Receives Dean’s Award for Mentorship of Undergraduate Research

    Tuesday, April 30, 2019

    This award recognizes faculty members who have excelled in nurturing undergraduate students’ desires and abilities to conduct meaningful research. This year SAS honors Ivan Dmochowski, the Alan MacDiarmid Term Professor of Chemistry, who is known for providing the undergraduates in his lab with exceptional opportunities to conduct long-term independent research and to publish co-authored research papers in prestigious journals.

  • Ivan Dmochowski Named Alan MacDiarmid Term Professor

    Tuesday, April 2, 2019

    Ivan Dmochowski, professor of chemistry, has been named the Alan MacDiarmid Term Professor of Chemistry. Dr. Dmochowski’s laboratory develops chemical and biophysical tools to study complex biological systems, including new technologies for biomolecular imaging, identifying proteins and RNA molecules important in brain function, and fabricating functional bio-nanomaterials. He has collaborations with many researchers at Penn and throughout the United States, Europe and Asia.

  • Penn Bioengineers: Cells Control Their Own Fate by Manipulating their Environment

    Wednesday, March 27, 2019

    As different as muscle, blood, brain and skin cells are from one another, they all share the same DNA. Stem cells’ transformation into these specialized cells — a process called cell fate determination — is controlled through various signals from their surroundings. A recent Penn Engineering study suggests that cells may have more control over their fate than previously thought. Jason Burdick, Robert D. Bent Professor of Bioengineering, and Claudia Loebel, a postdoctoral researcher in his lab, led the study. Their study was published in Nature Materials.

  • Michael Mitchell Wins Controlled Release Society T. Nagai Award

    Tuesday, March 19, 2019

    Michael Mitchell, Skirkanich Assistant Professor of Innovation in the Department of Bioengineering, is the recipient of the Controlled Release Society (CRS) 2019 T. Nagai Postdoctoral Research Achievement Award, which comes with a $3,000 honorarium. The sole recipient of this award, Mitchell was recognized for his work on engineering controlled release technologies for cancer gene therapy and immunotherapy. He will receive the award at the 2019 CRS annual meeting this July in Valencia, Spain.

  • Daeyeon Lee Named 2019 Penn Fellow

    Monday, March 18, 2019

    Daeyeon Lee, professor in the Department of Chemical and Biomolecular Engineering, has been named a 2019 Penn Fellow. The Penn Fellows program is aimed at giving faculty members the opportunity to build their leadership skills and meet with academic leaders throughout the University. Lee and his team at the Soft Materials Research and Technology lab focus on how nano- and micro-scale materials can assemble into macroscopic structures with useful properties and functionality.

  • Portonovo Ayyaswamy Named American Society of Mechanical Engineers Honorary Member

    Monday, March 18, 2019

    Ayyaswamy was selected “for exceptional contributions to mechanical engineering through a career marked with seminal and groundbreaking research scholarship, which has engendered transformational technology transfer for diverse applications; and for exemplary professional service to the worldwide scientific and practicing thermal engineering community.” The formal presentation of this award took place at the Honors Assembly on Monday, November 12, 2018 during the ASME Mechanical Engineering Congress & Exposition in Pittsburgh, Pennsylvania.

  • Christopher Murray Elected to National Academy Of Engineering

    Thursday, February 7, 2019

    Christopher Murray, Richard Perry University Professor and Professor in the Department of Materials Science and Engineering, has been elected to the National Academy of Engineering (NAE) “for invention and development of solvothermal synthesis of monodisperse nanocrystal quantum dots for displays, photovoltaics and memory”

  • Michael Mitchell Receives BMES Rising Star Award

    Thursday, January 17, 2019

    Michael Mitchell, Skirkanich Assistant Professor of Innovation in the Department of Bioengineering, has received a Rising Star Award in Cellular and Molecular Bioengineering from the Biomedical Engineering Society. One of six early-stage investigators from across the nation to receive the honor, Mitchell was recognized for his work on engineering delivery technologies for cancer gene therapy and immunotherapy, which is helping to lay the foundation for a new class of therapeutic strategies against hematologic cancers such as multiple myeloma and leukemia.

  • Dan Huh Wins 2018 Lush Science Prize for Organ-on-a-Chip Work

    Wednesday, November 28, 2018

    Bionengineering’s Dan Huh and his BIOLines research group were awarded the 2018 Lush Science Prize for work on organ-on-a-chip devices. The cosmetic company’s prize is designed to encourage work on alternatives to animal testing; Huh’s eye-on-a-chip embodied the themes of its 2018 Conference in Berlin.

  • Three Penn Engineers Recognized as APS Fellows

    Monday, November 19, 2018

    The American Physical Society annually recognizes a small percentage of its membership as APS Fellows for excelling in their specialties. This year’s Fellows from Penn include three Engineering professors: John Crocker, Chinedum Osuji and Shu Yang. Yang, Professor of Materials Science and Engineering, Chemical and Biomolecular Engineering, was cited for contributions to the geometric design and controlled assembly of soft matter.

  • Penn Engineers’ Liquid Crystal Force Fields Enable New Kind of Microrobotics

    Monday, November 12, 2018

    A new study, published in Nature Communications, shows how simple glass particles can be instructed to follow sophisticated trajectories, which arise from their interactions with a liquid crystalline environment. Though the particles in question have no moving parts or internal energy sources, they can be controlled much like robots. The study was led by Kathleen Stebe, Richer & Elizabeth Goodwin Professor in the Department of Chemical and Biomolecular Engineering, former Stebe lab member Francesca Serra.

  • Johnson & Johnson Start-Up Incubator JPOD Hosts Five Engineering Companies

    Tuesday, November 6, 2018

    Andrew Tsourkas, professor in the Department of Bioengineering, is an expert in designing nanoparticles that can locate and bind to tumors. Along with colleagues from the Perelman School of Medicine, Jay Dorsey and David Cormode, Tsourkas founded PolyAurum, a spin-off company that uses tiny polymer-coated gold particles to improve radiation treatments for cancer.

  • Seven Penn Researchers Receive NIH Director’s Awards [Michael Mitchell - New Innovator Award]

    Tuesday, October 2, 2018

    Michael Mitchell, PhD, the Skirkanich Assistant Professor of Innovation in Penn’s School of Engineering and Applied Science’s Department of Bioengineering, will also receive $2.4 million to further his lab’s work employing tools and concepts from cellular engineering, biomaterials science, and drug delivery to understand and therapeutically target complex biological barriers in the body. His lab applies their research findings — and the drug delivery technologies developed — to a range of human health applications, including cancer metastasis, immunotherapy, and gene editing. Among his research interests, Mitchell designs drug delivery technologies to engineer cells in the bone marrow and blood vessels as a way of gaining control over how and why cancer disseminates throughout the body, as well as to engineer immune cells for immunotherapy and vaccination. Grant ID: DP2-TR002776

  • The 2018 Penn Medicine Awards of Excellence Recipients for Research include: Stanley N. Cohen Biomedical Research Award to Roger A. Greenberg, MD, PhD, of the Department of Cancer Biology.

    Wednesday, September 12, 2018

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Center for Targeted Therapeutics and Translational Nanomedicine

Institute for Translational Medicine and Therapeutics (ITMAT)
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