10 11 1 7 1b 3a 49 38 5f 3 5 b 3 5 5 11 86 Trainee Spotlights | ITMAT Education and Training | Perelman School of Medicine at the University of Pennsylvania 5 5 5 4f 6e 5 5 5 5 9 64 58 47 1 5 5 5 11 9 5 5 5e 1 5 5 66 6a 1 19 5f 1 4f 5 5 5 9 5 9 8 1 6 5 5 9 5 7 a 1 5 d
9 9 37
3 1e a 22 a a 24
6f
Institute for Translational Medicine and Therapeutics
32 7
1 5 1f
2c 33 ITMAT Education and Training 8 b d
7 5 7 1 2 5 c
a 5 9 19 5 e
5 5 5 49 1 5 9 1c
9 21
d d 35
5e
Clinical Trialist Training Program
13
19 d d 19 d 2e
11 11 1 3a 12 21 11 11 2b
15 15 15 29 29 2f
19 31 31
9 37
49

4c Trainee Spotlights

21 1b
29 15 15 21 29 33
1d 17 3a
1b 1b 1b 1f 57 21 21 25 49 5 25 49 25 1f 1f 49 25 1 1 1 9 28
a
d e
49

Past Trainees

21
    1 38
  • 5 23
    9 1 1 1 1 1 1 1 1 1 a d 85 Photo of Ryan Carey, MD b 1 9 9 b
    5 22
    38

    Ryan Carey, MD

    c

    41 CTTP Trainee 2024-2026
    9 9 9 9 d

    33 b
    5 d 3d
    10 40 Close modal dialog 28 51 5b 18 11 30
    11 1 1 1 1 1 1 1 1 1 a d 85 Photo of Ryan Carey, MD b 1 40

    Ryan Carey, MD

    14

    49 CTTP Trainee 2024-2026
    11 11 11 11 15

    18f

    Ryan Carey, MD, is a head and neck oncologic and reconstructive surgeon-scientist and Assistant Professor of Otorhinolaryngology at the University of Pennsylvania. His clinical practice focuses on the care of patients with complex head and neck cancers, while his research program is dedicated to developing novel therapeutic strategies through translational cancer research.

    1e8

    Ryan applied to CTTP because he wanted formal training in clinical and translational research that would help him bridge laboratory discoveries with clinical trial development and ultimately improve outcomes for patients with head and neck cancer. Through the program, he gained valuable experience in clinical trial design, biostatistics, regulatory science, and translational research, while also benefiting from mentorship and a collaborative community of fellow investigators.

    217

    Since completing CTTP, Ryan has established an NIH-funded translational research program focused on taste receptor signaling, tumor immunology, and novel therapeutic strategies for head and neck cancer. He currently leads investigator-initiated clinical trials and translational research studies, while also serving as an investigator on industry-sponsored clinical trials. Moving forward, he aims to continue translating discoveries from the laboratory into innovative therapies that improve outcomes for patients with cancer.

    13
    f
    e     6
    • 1 1 38
  • 5 23
    9 1 1 1 1 1 1 1 1 1 a d 7c Photo of Gaia Coppock, MD b 1 9 9 b
    5 22
    3a

    Gaia Coppock, MD

    c

    42 CTTP Trainee, 2020-2022
    9 9 9 9 d

    33 b
    5 d 3d
    10 40 Close modal dialog 28 51 5b 18 11 30
    11 1 1 1 1 1 1 1 1 1 a d 7c Photo of Gaia Coppock, MD b 1 42

    Gaia Coppock, MD

    14

    4a CTTP Trainee, 2020-2022
    11 11 11 11 15

    af

    Current Position: Assistant Professor; Renal, Electrolyte, and Hypertension Division, University of  Pennsylvania Perelman School of Medicine

    575

    Gaia applied to the program because she has a background in basic science immunology research and wanted to find an avenue to use that knowledge in more of a clinical space. Her formal project in the Clinical Trialist Training Program was working on the TRIDENT2.0 study, which is looking at the impact on gene expression in people with diabetic kidney disease who are being treated with SGLT2 inhibitors. During her program, she worked on the IRB proposal, CRFs, and MOP. She shared "being a [CTTP participant] during the height of the COVID pandemic taught me some important lessons about navigating trial development with limited resources." She took classes during the program to understand elements of study design like designing a budget, which she thought were incredibly useful when seeing budget negotiations happen in real time. As she's met people in the clinical trials space, they've shared with her they had to learn on the job. She shared "while hands on experience is an important part of every training program, the CTTP allowed me the chance to develop a strong foundation through coursework and mentorship that broke down many of the barriers that I otherwise would have faced in trying to learn how to navigate this process. I am very grateful for the mentorship and structure that is provided during that time so that I could grow into my current role."

    71

    Check out Gaia's publications on PubMed.

    13
    f
    e     6
    • 1 1 38
  • 5 23
    9 1 1 1 1 1 1 1 1 1 a d ae Photo of Archna Bajaj, MD, MSCE b 1 9 9 b
    5 22
    40

    Archna Bajaj, MD, MSCE

    c

    42 CTTP Trainee, 2018-2020
    9 9 9 9 d

    33 b
    5 d 3d
    10 40 Close modal dialog 28 51 5b 18 11 30
    11 1 1 1 1 1 1 1 1 1 a d ae Photo of Archna Bajaj, MD, MSCE b 1 48

    Archna Bajaj, MD, MSCE

    14

    4a CTTP Trainee, 2018-2020
    11 11 11 11 15

    ca

    Current Position: Assistant Professor, Department of Medicine, Division of Translational Medicine and Human Genetics, University of  Pennsylvania Perelman School of Medicine

    3c9

    Archna applied to the program because she was interested in receiving more formal training to become a clinical trialist, and for the protected time it offered her to work on an early phase trial to get an in-depth experience in trial design and development. She is working on development of a phase I first-in-human clinical trial for a gene therapy product for LCAT deficiency — a very rare genetic disorder of cholesterol metabolism with high morbidity/mortality from early and progressive renal sequelae of the disease. She is working on the pre-IND submission, including development of the trial design which will involve using a non-traditional adaptive design given the rarity of the disorder. She has also found the fellowship to "be helpful for connecting with other fellows who share an interest in clinical trials and share experiences on trial development and the resources and/or educational opportunities we've each found to be useful."

    7d

    Check out Archna's publications on Pub Med.

    13
    f
    e     6
    • 1 1 38
  • 5 23
    9 1 1 1 1 1 1 1 1 1 a d a8 Photo of David Fajgenbaum, MD, MBA, MSc b 1 9 9 b
    5 22
    48

    David Fajgenbaum, MD, MBA, MSc

    c

    42 CTTP Trainee, 2018-2020
    9 9 9 9 d

    33 b
    5 d 3d
    10 40 Close modal dialog 28 51 5b 18 11 30
    11 1 1 1 1 1 1 1 1 1 a d a8 Photo of David Fajgenbaum, MD, MBA, MSc b 1 50

    David Fajgenbaum, MD, MBA, MSc

    14

    4a CTTP Trainee, 2018-2020
    11 11 11 11 15

    518

    Current Position: Assistant Professor, Department of Medicine, Division of Translational Medicine and Human Genetics, University of  Pennsylvania Perelman School of Medicine

    David applied to the program because he identified a need for mentorship and protected time to effectively run a clinical trial. Data that he  generated using orthogonal basic and translational research techniques suggested that there was increased mammalian Target of Rapamycin  (mTOR) signaling in idiopathic multicentric Castleman disease (iMCD) and that it may be a critical therapeutic target for the disease. Off-  label use of an mTOR inhibitor in iMCD suggested that it may be a safe and effective approach for treatment-refractory patients. David is currently testing this hypothesis in a clinical trial with support from the Clinical Trials Fellowship. The program "has provided me with critical mentorship to prepare for launching my first interventional clinical trial as a PI. I have received targeted feedback on launch plans and enrollment strategies." David was able to take a bioinformatics course during his protected time, that the fellowship provided. He has also “enjoyed getting to know and connect with other ITMAT Clinical Trials Fellows."

    82

    Check out David's publications on Pub Med.

    13
    f
    e     6
    • 1 1 38
  • 5 23
    9 1 1 1 1 1 1 1 1 1 a d a6 Photo of Ethan Weinberg, MD, MS b 1 9 9 b
    5 22
    40

    Ethan Weinberg, MD, MS

    c

    42 CTTP Trainee, 2018-2020
    9 9 9 9 d

    33 b
    5 d 3d
    10 40 Close modal dialog 28 51 5b 18 11 30
    11 1 1 1 1 1 1 1 1 1 a d a6 Photo of Ethan Weinberg, MD, MS b 1 48

    Ethan Weinberg, MD, MS

    14

    4a CTTP Trainee, 2018-2020
    11 11 11 11 15

    cf

    Current Position: Assistant Professor in Clinical Medicine, Department of Medicine, Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine

    3b7

    Ethan is interested in being a site PI for industry-sponsored trials and composing single-center and multi-center investigator-initiated clinical  trials. Since beginning the Clinical Trials Fellowship, he has opened a therapeutic trial for the use of ursodeoxycholic acid in hepatic sarcoid  (https://clinicaltrials.gov/ct2/show/NCT03602976) and successfully recruited subjects into the study. He is taking one graduate level course per  semester on clinical trials and has been able to publish some of his work from these classes. The Clinical Trialist Training Program has provided the  resources and salary-support for him to pursue an investigator-initiated clinical trial into a rare disease, hepatic sarcoid, that is understudied.  "This work and my studies would not have been possible without the support of this program."

    7e

    Check out Ethan's publications on Pub Med.

    13
    f
    e     6
    • 16
7
1 3c

Do you want to learn more about their experience?

124

The participants would be happy to meet with those interested in learning more about their experience in the program. Contact Jessica German to be connected.

2e

 

21 3b 21 25 1d
17 15 1c
a 1 16 27 16 2e 19 16 15 1 15 12 14
e 11 21 11 13
d
b
9 1 1c 1 1 4c 1 8 1 7 0